VGLUT2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityVGLUT2
Clone[S29-29]
Host SpeciesMouse
Reactive Speciesmouse, rat
IsotypeIgG1
FormatATTO 488 conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsImmunohistochemistry (IHC), Western Blot (WB)
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DescriptionBackground Info: Detects ~60kDa. Scientific Background: The ATP-dependent, chloride-sensitive vesicular glutamate transporters (VGLUT) include BNPI (VGLUT1), VGLUT2 (DNPI) and VGLUT3. The brain expresses BNPI (brain specific Na -dependent inorganic phosphate (Pi) cotransporter) and VGLUT2 in a complementary fashion. The telencephalic regions express BNPI, whereas the lower brainstem and diencephalic regions express VLGUT2. Rat pinealocytes express both BNPI and VGLUT2. The striatum, hippocampus, cerebral cortex and raphe nuclei express VGLUT3 in a small number of neurons. Pancreatic alpha and beta cells express BNPI and VGLUT2 in response to glucose concentrations. Human VGLUT3 shares a 72% sequence homology with VLGUT2 and BNPI.
Immunogenn/a
Other Names[Differentiation associated BNPI; DNPI; SLC17A6; Solute carrier family 17 member 6; Vesicular glutamate transporter 2; Differentiation associated Na dependent inorganic phosphate cotransporter], [Slc17a6; Slc17a6; Dnpi; Vglut2; Dnpi; Vglut2; VGluT2]
Gene, Accession #Gene ID: 84487, NCBI: NP_445879.1, UniProt: Q9JI12
Catalog #MBS800454
Price$440
Order / More InfoVGLUT2 Antibody from MYBIOSOURCE INC.
Product Specific References1. Aihara Y., et al. (2000) J Neurochem. 74: 2622-2625. 2. Kaneko T., and Fujiyama F. (2002) Neurosci Res. 42: 243-250. 3. Gras C., et al. (2002) J Neurosci. 22: 5442-5451. 4. Takamori S., Malherbe P., Broger C., and Jahn R. (2002) EMBO Rep. 3: 798-803. 5. Morimoto R., Hayashi M., Yatsushiro S., Otsuka M., Yamamoto A., and Moriyama Y. (2003) J Neurochem. 84: 382-391. 6. Bai L., Zhang X., and Ghishan F.K. (2003) Am. J. Physiol. Gastrointest. Liver Physiol. 284: G808-814.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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