Edit |   |
---|---|
Antigenic Specificity | HP1alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.025 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect CBX5 in human samples. Background: CBX5/HP1 alpha is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involved in the formation of a functional kinetochore through interaction with MIS12 complex proteins. |
Immunogen | Immunogen: Polyclonal antibody raised in rabbit against human HP1alpha (Heterochromatin protein 1 homolog alpha), using the full length recombinant GST tagged protein. Positive Control: Western blot: HeLa cells, IF: HeLa cells. |
Other Names | [HP1alpha; HP1A], [CBX5; CBX5; HP1; HP1A; HEL25; HP1A; HP1 alpha] |
Gene, Accession # | [HP1alpha], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973 |
Catalog # | MBS841045 |
Price | $325 |
Order / More Info | HP1alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |