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Antigenic Specificity | Human CCR3 |
Clone | [7F12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) - Formalin, Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CCR-3 or CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4. CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function. In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells. CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammat |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with 293 cells transfected with human CCR3. |
Other Names | [CCR3; CKR3; CD193; CMKBR3; CC-CKR-3], [CCR3; CCR3; CKR3; CD193; CMKBR3; CC-CKR-3; CMKBR3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3] |
Gene, Accession # | [CCR3], Gene ID: 1232, NCBI: NP_001828.1, UniProt: P51677 |
Catalog # | MBS691030 |
Price | $490 |
Order / More Info | Human CCR3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |