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Antigenic Specificity | Polymyxin B |
Clone | [9G252] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgM |
Format | supernatant |
Size | 1 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes Polymyxin B. Binds to free Polymyxin B as well as to Polymyxin B already bound to LPS. The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo. Monoclonal antibody enables the possibilit |
Immunogen | Immunogen: Whole bacteria of the Re chemotype of S. minnesota |
Other Names | [-Polymyxin B], [pmrD] |
Gene, Accession # | Gene ID: 1248860, NCBI: NP_456847.1 |
Catalog # | MBS608181 |
Price | $780 |
Order / More Info | Polymyxin B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |