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Antigenic Specificity | TFAP2C (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TFAP2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 114-147 amino acids from the central region of human TFAP2C. Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Transcription factor AP-2 gamma; AP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1; TFAP2C] |
Gene, Accession # | [TFAP2C], Gene ID: 7022, NCBI: NP_003213.1, UniProt: Q92754 |
Catalog # | MBS9216400 |
Price | $150 |
Order / More Info | TFAP2C (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Williamson J.A.,et al.Genomics 35:262-264(1996).McPherson L.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:4342-4347(1997).Haselton M.D.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).Deloukas P.,et al.Nature 414:865-871(2001). |