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Antigenic Specificity | TNFRSF10C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNFRSF10C antibody detects endogenous levels of total TNFRSF10C. Description: The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1, 2). The receptors are activated by a family of cytokines that include TNF, FasL, and TRAIL. They are characterized by a highly conserved extracellular region containing cysteine-rich repeats and a conserved intracellular region of about 80 amino acids termed the death domain (DD). The DD is important for transducing the death signal by recruiting other DD containing adaptor proteins (FADD, TRADD, RIP) to the death-inducing signaling complex (DISC), resulting in activa |
Immunogen | Immunogen: A synthesized peptide derived from human TNFRSF10C Subcellular Location: Cell Membrane and Cytoplasmic Tissue Specificity: Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart. |
Other Names | [Antagonist decoy receptor for TRAIL/Apo 2L; CD263; Cytotoxic TRAIL receptor 3; DCR1; DCR1 TNFR; Decoy Receptor 1; Decoy TRAIL receptor without death domain; LIT; Lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF related apoptosis inducing ligand receptor 3; TNF-re ated apoptosis inducing ligand receptor 3; TNFRSF10C; TRAIL R3; TRAIL receptor 3; TRAILR3; TRID; Tumor necrosis factor receptor superfamily member 10C; Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain] |
Gene, Accession # | [TNFRSF10C], Gene ID: 8794, NCBI: NP_003832.2, UniProt: O14798 |
Catalog # | MBS9606930 |
Price | $240, $280 |
Order / More Info | TNFRSF10C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |