Edit |   |
---|---|
Antigenic Specificity | ROR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [NTRKR1; dJ537F10.1], [ROR1; ROR1; NTRKR1; dJ537F10.1; NTRKR1] |
Gene, Accession # | [ROR1], Gene ID: 4919, NCBI: Q01973.2, UniProt: Q01973 |
Catalog # | MBS129572 |
Price | $200, $275, $430 |
Order / More Info | ROR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |