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Antigenic Specificity | Phospho-Rac1/cdc42 (Tyr64) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Rac1/cdc42 (Tyr64) Antibody detects endogenous levels of Rac1/cdc42 only when phosphorylated at Tyr64. Description: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal n |
Immunogen | Immunogen: A synthesized peptide derived from human Rac1/cdc42 around the phosphorylation site of Tyr64. |
Other Names | [CDC42; CDC42_HUMAN; CDC42Hs; Cell division control protein 42 homolog; Cell division cycle 42 (GTP binding protein 25kDa); Cell division cycle 42; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K; G25K GTP-binding protein; Growth regulating protein; GTP binding protein 25kDa; Small GTP binding protein CDC42; TKS] |
Gene, Accession # | [Rac1/cdc42], Gene ID: 998, NCBI: NP_001782.1, UniProt: P60953 |
Catalog # | MBS9610690 |
Price | $225, $280, $340 |
Order / More Info | Phospho-Rac1/cdc42 (Tyr64) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |