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Antigenic Specificity | ITCH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the negative regulation of MAVS-dependent cellular antiviral responses. Ubiquitinates MAVS through 'Lys-48'-linked conjugation resulting in MAVS proteosomal degradation. Involved in the regulation of apoptosis and reactive oxygen species levels through the ubiquitination and proteosomal degradation of TXNIP. Mediates the antiapoptotic activity of epidermal growth factor through the ubiquitination and proteosomal degradation of p15 BID. |
Immunogen | Immunogen: A synthesized peptide derived from human ITCH |
Other Names | [ADMFD; AIF4; AIP4; Atrophin 1 interacting protein 4; Itchy homolog E3 ubiquitin protein ligase; NAPP1; NFE2 associated polypeptide 1; Ubiquitin protein ligase ITCH] |
Gene, Accession # | [ITCH], Gene ID: 83737, NCBI: NP_001244066.1, UniProt: Q96J02 |
Catalog # | MBS8543369 |
Price | $280 |
Order / More Info | ITCH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |