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Antigenic Specificity | CTNND1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CTNND1 protein. Catenin d-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function (1). Catenin d-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion (2). Catenin d-1 has both positive and negative effects on cadherin-mediated adhesion (3). Actin dynamics are also regulated by catenin d-1, which modulates RhoA, Rac, and cdc42 proteins (1). Analogous to b-catenin, |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CTNND1. |
Other Names | [CAS; CTNND; KIAA0384; P120CAS; P120CTN] |
Gene, Accession # | [CTNND1], Gene ID: 1500, NCBI: NP_001078927.1, UniProt: O60716 |
Catalog # | MBS9409753 |
Price | $255 |
Order / More Info | CTNND1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |