ITGB6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityITGB6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: ITGB6 antibody detects endogenous levels of total ITGB6. Function: Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881).Subunit Structure: Heterodimer of an alpha and a beta subunit. Beta-6 associates with alpha-V. Interacts with FLNB. Interacts with HAX1. ITGAV:ITGB6 interacts with FBN1 (PubMed:17158881).Similarity: Belongs to the integrin beta chain family.
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Membrane. Predicted Cross Reactivity: Pig, Horse, Rabbit, Dog Similarity: Pig (89%), Horse (89%), Rabbit (89%), Dog (89%)
Other Names[Integrin beta-6; ITB6_HUMAN; ITGB6]
Gene, Accession #[ITGB6], Gene ID: 3694, NCBI: NP_000879.2, UniProt: P18564
Catalog #MBS9604057
Price$240, $280
Order / More InfoITGB6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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