Aposcreen Annexin V-PE Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAposcreen Annexin V-PE
Clonepolyclonal
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size100 tests
Concentrationn/a
ApplicationsBlocking Annexin V-conjugates, Flow Cytometry, Fluorescence Microscopy
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DescriptionA number of changes in cell structure occur during apoptosis. One major change is the loss of membrane phospholipid asymmetry, with translocation of phosphatidylserine (PS) from the inner leaflet of the phospholipid bilayer to the external surface.1 Annexin V (Mr 36-kDa), a member of the annexin family of calcium-dependent phospholipid binding proteins, has a high affinity for PS-containing phospholipid bilayers.2,3 When PS is exposed on the extracellular face of a cell membrane, annexin V binds with an affinity of approximately 7 nM.4 Fluorochrome conjugates of annexin V can be used to monitor changes in cell membrane phospholipid asymmetry,5-8 thereby providing a convenient tool for detection of apoptotic cells. ApoScreen Annexin V is a l
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS670377
Price$250
Order / More InfoAposcreen Annexin V-PE Antibody from MYBIOSOURCE INC.
Product Specific References1. Fadok, V.A. et al. 1992. J. Immunol. 148:22072. Tait, J.F., et al. 1989. J. Biol. Chem. 264:7944.3. Andree, H.A., et al. 1990. J. Biol. Chem. 265:4923.4. Thiagarajan, P., et al. 1990. J. Biol. Chem. 265:17420.5. Dachary, P.J., et al. 1993. Blood 81:2554.6. Koopman, G., et al. 1994. Blood 84:1415.7. Martin, S.J., et al. 1995. J. Exp. Med. 182:1545.8. Wood, B.L., et al. 1996. Blood 88:1873.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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