TENS3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TENS3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TENS3 antibody detects endogenous levels of total TENS3. Function: May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity).Subunit Structure: EGF promotes the interaction with EGFR. Interacts with PTK2/FAK1 and BCAR1. Tyrosine phosphorylation is critical for these interactions.Post-translational Modifications: EGF/epidermal growth factor induces tyrosine phosphorylation in a time-and dose-dependent manner. |
| Immunogen | Immunogen: A synthesized peptide derived from human TENS3 Subcellular Location: Cell Junction, Focal Adhesion. Tissue Specificity: Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level). Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial cells. Expression seems to be down-regulated in thyroid tumor tissues and in anaplastic carcinomas. |
| Other Names | [TEM 6; TEM6; TENS 1; TENS 3; TENS1; TENS3; TENS3_HUMAN; Tensin-3; tensin-like SH2 domain containing 1; Tensin-like SH2 domain containing protein 1; Tensin-like SH2 domain-containing protein 1; Tensin-like SH2 domain-containing protein 1; thyroid specific PTB domain protein; TNS 3; TNS3; TPP; Tumor endothelial marker 6] |
| Gene, Accession # | [TENS3], Gene ID: 64759, NCBI: NP_073585.8, UniProt: Q68CZ2 |
| Catalog # | MBS9609155 |
| Price | $240, $280 |
| Order / More Info | TENS3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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