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Antigenic Specificity | IQGAP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.7mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1, 631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's dise |
Immunogen | Immunogen: Recombinant protein of human IQGAP3 Calculated Molecular Weight: 185kDa |
Other Names | [IQGAP3; Ras GTPase-activating-like protein IQGAP3; ras GTPase-activating-like protein IQGAP3; IQ motif containing GTPase activating protein 3] |
Gene, Accession # | [IQGAP3], Gene ID: 128239, NCBI: AAP06954.1 |
Catalog # | MBS2525293 |
Price | $110, $150, $225 |
Order / More Info | IQGAP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |