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Antigenic Specificity | SIRT3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SIRT3 protein. NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.Bechtel S., BMC Genomics 8:399-399(2007).Schwer B., J. Cell Biol. 158:647-657(2002).Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human SIRT3. |
Other Names | [NAD-dependent deacetylase sirtuin-3; mitochondrial; SIR2-like protein 3; hSIRT3; SIRT3] |
Gene, Accession # | [SIRT3], Gene ID: 23410, NCBI: NP_001017524.1, UniProt: Q9NTG7 |
Catalog # | MBS9406445 |
Price | $200, $255 |
Order / More Info | SIRT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |