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Antigenic Specificity | Apobec1 (N-term), 7-36 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Apobec1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human Apobec1. APOBEC1 is involved in the production of apolipoprotein B (apoB)-48 from apoB-100. The gene spans 18 kb and contains five exons, all of which are translated. Alternative splicing produces a variant transcript that lacks exon 2 and encodes a novel 36-amino acid peptide. The exon 2-skipped transcript accounts for approximately 50% of APOBEC1 mRNA in the adult small intestine and up to 90% of APOBEC1 mRNA in the developing gut. Exon 2-skipping may thus be a quantitatively important mechanism for regulating the expression of this gene in the gastrointestinal tract. |
Immunogen | n/a |
Other Names | [C->U-editing enzyme APOBEC-1; 354-; Apolipoprotein B mRNA-editing enzyme 1; HEPR; APOBEC1] |
Gene, Accession # | [APOBEC1], Gene ID: 339, NCBI: NP_001635.2, UniProt: P41238 |
Catalog # | MBS9200910 |
Price | $165, $370 |
Order / More Info | Apobec1 (N-term), 7-36 Antibody from MYBIOSOURCE INC. |
Product Specific References | Blanc, V., et al., J. Biol. Chem. 278(42):41198-41204 (2003). Chester, A., et al., EMBO J. 22(15):3971-3982 (2003). Wedekind, J.E., et al., Trends Genet. 19(4):207-216 (2003). Mukhopadhyay, D., et al., Am. J. Hum. Genet. 70(1):38-50 (2002). Dance, G.S., et al., J. Biol. Chem. 277(15):12703-12709 (2002). |