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Antigenic Specificity | Spectrin beta III (SPTBN2) |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin) and spectrin I (also designated fodrin) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectri |
Immunogen | Immunogen: Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary) |
Other Names | [Beta III spectrin; SCA5; Spectrin beta chain brain 2; Spectrin beta non-erythrocytic 2; Spectrin non-erythroid beta chain 2; Spinocerebellar ataxia 5; SPTBN2] |
Gene, Accession # | [SPTBN2], Gene ID: 6712, NCBI: NP_008877.1, UniProt: O15020 |
Catalog # | MBS4381268 |
Price | $190, $340, $340 |
Order / More Info | Spectrin beta III (SPTBN2) Antibody from MYBIOSOURCE INC. |
Product Specific References | Michael C. Stankewich, et al. PNAS, 1998. 95 (24) 14158-14163. |