TESC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTESC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, horse, rabbit, dog
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: TESC Antibody detects endogenous levels of TESC. Description: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.Subunit Structure: Monomer. Homodimer; disulfide-linked (By similarity). Interacts
ImmunogenImmunogen: A synthesized peptide derived from human TESC. Tissue Specificity: Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level). Abundantly expressed in heart. Also expressed at a lower level in adult testis and salivary gland, and in the placenta.
Other Names[1010001A17Rik; Calcineurin B homologous protein 3; CHP3; FLJ20607; MGC117906; OTTHUMP00000185561; OTTMUSP00000023573; TE 1; Tescalcin; TSC]
Gene, Accession #[TESC], Gene ID: 54997, NCBI: NP_001161797.1, UniProt: Q96BS2
Catalog #MBS9611520
Price$240, $280
Order / More InfoTESC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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