Glial fibrillary acidic protein / GFAP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Glial fibrillary acidic protein / GFAP |
| Clone | [6F2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 6F2 reacts exclusively with glial fibrillary acidic protein which is present in astrocytes in the central nervous system and Schwann cells. GFAP (55 kD) is selectively loCated in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the prolifeRation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer's disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in |
| Immunogen | Source Note: 6F2 is a Mouse monoclonal IgG1 antibody derived by fusion of Mouse myeloma cells with spleen cells from a Mouse immunized with glial fibrillary acidic protein from Human brain. |
| Other Names | [glial fibrillary acidic protein; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein], [GFAP; GFAP; FLJ45472; GFAP] |
| Gene, Accession # | Gene ID: 2670, UniProt: P14136 |
| Catalog # | MBS570104 |
| Price | $415 |
| Order / More Info | Glial fibrillary acidic protein / GFAP Antibody from MYBIOSOURCE INC. |
| Product Specific References | Van Muijen, G. N., Ruiter, D. J., and Warnaar, S. O. (1987). Coexpression of intermediate filament polypeptides in Human fetal and adult tissues, Lab Invest 57, 359-69. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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