Clostridium Difficile (Toxin A) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Clostridium Difficile (Toxin A) |
| Clone | [253/422] |
| Host Species | Mouse |
| Reactive Species | Clostridium difficile |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb reacts with C. difficile Toxin A, but not with Cholera subunit a, Cholera toxin, Pseudomonas aeruginosa exotoxin A, H-LT, P-LT. Clostridium difficile is a major nosocomial pathogen that causes antibiotic- associated colitis. Clostridium difficile mediates inflammatory diarrhea by releasing two large protein enterotoxins (Toxin A and Toxin B) that are able to disrupt intestinal epithelial cells via their transferase activity and ability to monoglucosylate members of the Rho family. Clostridium difficile Toxin A is a toxin that is composed of 39 repeats that are responsible for binding to intestinal epithelial cell surface carbohydrates. Clostridium difficile Toxin A causes significant apoptosis of colonocytes which contributes to th |
| Immunogen | Immunogen: C. difficile Toxin A |
| Other Names | [Clostridium difficile; C. difficile; tcdA; toxA] |
| Gene, Accession # | NCBI: P16154.2, UniProt: P16154 |
| Catalog # | MBS4381469 |
| Price | $190, $340, $340 |
| Order / More Info | Clostridium Difficile (Toxin A) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kim, H., et al. 2005. Gastroenterology 129: 1875-1888. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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