SQSTM1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySQSTM1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSQSTM1 Antibody: SQSTM1/p62 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NF-κB by TNF-α, nerve growth factor (NGF) and interleukin-1. SQSTM1/p62, a co-interacting protein of the atypical PKC isoforms, has a UBA domain at its C-terminal end, which binds non-covalently to polyubiquitin chain. SQSTM1's UBA domain is necessary for recruitment of polyubiquitin and aggresome formation. SQSTM1 may play a role in titin/TTN downstream signaling in muscle cells and may be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels. Mutations in the ubiquitin-associated (UBA) domain of SQSTM1 commonly cause Paget's disease
ImmunogenImmunogen: SQSTM1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human SQSTM1. Buffer: SQSTM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[SQSTM1; p60; p62; A170; OSIL; PDB3; ZIP3; p62B; ORCA; Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; sequestosome 1], [SQSTM1; SQSTM1; p60; p62; A170; OSIL; PDB3; ZIP3; p62B; ORCA; OSIL; EBIAP; p60]
Gene, Accession #[SQSTM1], Gene ID: 8878, NCBI: Q13501.1, UniProt: Q13501
Catalog #MBS151473
Price$375
Order / More InfoSQSTM1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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