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Antigenic Specificity | JHDM1D (Center), 290-316 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This JHDM1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the Central region of human JHDM1D. JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3. |
Immunogen | n/a |
Other Names | [Lysine-specific demethylase 7A; 11411-; JmjC domain-containing histone demethylation protein 1D; Lysine-specific demethylase 7; KDM7A; JHDM1D; KDM7; KIAA1718] |
Gene, Accession # | [KDM7A], Gene ID: 80853, NCBI: NP_085150.1, UniProt: Q6ZMT4 |
Catalog # | MBS9202680 |
Price | $165, $370 |
Order / More Info | JHDM1D (Center), 290-316 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |