Edit |   |
---|---|
Antigenic Specificity | RBBP5 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RBBP5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 451-485 amino acids from the C-terminal region of human RBBP5. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. |
Immunogen | n/a |
Other Names | [Retinoblastoma-binding protein 5; RBBP-5; Retinoblastoma-binding protein RBQ-3; RBBP5; RBQ3] |
Gene, Accession # | [RBBP5], Gene ID: 5929, NCBI: NP_001180201.1, UniProt: Q15291 |
Catalog # | MBS9207884 |
Price | $165, $370 |
Order / More Info | RBBP5 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Saijo M.,et al.Genomics 27:511-519(1995). Ota T.,et al.Nat. Genet. 36:40-45(2004). Gregory S.G.,et al.Nature 441:315-321(2006). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Hughes C.M.,et al.Mol. Cell 13:587-597(2004). |