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Antigenic Specificity | Human CD34 |
Clone | [CS37] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 tests |
Concentration | Titered for flow cytometry when used as indicated below. PBMc: Add 10 ul of MAB/10^6 PBMc in 100 ul PBS. Mix gently and incubate for 15 minutes at 2 degree to 8 degree c. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human Progenitor Cell Antigen (MW 115 K daltons) is found on normal peripheral blood lymphocytes, monocytes, granulocytes and platelets. CD34 is present on 1% or less of cells in normal human bone marrow. Human Progenitor Cell Antigen reacts with 30-70% of acute leukemias, as well as all TdT positive lymphocytes in bone marrow. |
Immunogen | Immunogen: CD34=Derived from the hybridization of mouse Sp2/O-Ag14 cells with spleen cells of BALB/c mice immunized with human cell line KG-1a |
Other Names | [CD34; Hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell antigen CD34; CD34 molecule], [CD34; CD34] |
Gene, Accession # | [CD34], Gene ID: 947, NCBI: AAB25223.1, UniProt: P28906 |
Catalog # | MBS397656 |
Price | $255 |
Order / More Info | Human CD34 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Antigenic Analysis of Hematopoiesis III. A Hematopoietic Progenitor Cell Antigen Defined by a Monoclonal Antibody raised against KG-1a cells Civin, C.I., Strauss,L.C., Broveal,C., Fackler,M.J., Schwartz,J.F., and Shaper,J.H., J. Immunol. 133,157,1984 2. Rapid isolation of human CD34 hematopoietic stem cells--purging of human tumor cells. Lebkowski JS; Schain LR; Okrongly D; Levinsky R; Harvey MJ; Okarma T Transplantation 1992 May;53(5):1011-9 3. Distribution of surface-membrane molecules on bone marrow and cord blood CD34 hematopoietic cells. Saeland S; Duvert V; Caux C; Pandrau D; Favre C; Valle A; Durand I; Charbord P; de Vries J; Banchereau J Exp Hematol 1992 Jan;20(1):24-33 4. CD34-positive cell proportions in peripheral blood correlate with colony-forming capacity. Fritsch G; Emminger W; Buchinger P; Printz D; Gadner H Exp Hematol 1991 Dec;19(11):1079-83 5. CD34 expression by stromal precursors in normal human adult bone marrow. Simmons PJ; Torok-Storb B Blood 1991 Dec 1;78(11):2848-53 6. Human CD34 HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis. Srour EF; Brandt JE; Briddell RA; Leemhuis T; van Besien K; Hoffman R Blood Cells 1991;17(2):287-95 7. Surface marker expression in acute myeloid leukaemia at first relapse. Thomas X; Campos L; Archimbaud E; Shi ZH; Treille-Ritouet D; Anglaret B; Fiere D Br J Haematol 1992 May;81(1):40-4 Product Specific References: 1. Gardner, J.P. et al. 'Robust, but transient expression of adeno-associated virus-transduced genes during human t lymphopoisis.' Blood, 1997, 90, 4854-4864. |