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Antigenic Specificity | FLT3 (Tyr591) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FLT3 antibody (Tyr591) detects endogenous levels of FLT3 only when phosphorylated at tyrosine 591. FLT3 is a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. |
Immunogen | Immunogen: FLT3 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human FLT3 around the phosphorylation site of tyrosine 591 (Y-F-YP-V-D) as the immunogen. |
Other Names | [Rabbit FLT3 (Tyr591); FLT3; FLT3; CD135; CD135 antigen; fetal liver kinase 2; FL cytokine receptor; FLK2; FLT-3; FLT3; FLT3 receptor tyrosine kinase; Fms-like tyrosine kinase 3; fms-related tyrosine kinase 3; growth factor receptor tyrosine kinase type III; Stem cell tyrosine kinase 1; STK-1; STK1; Tyrosine-protein kinase receptor FLT3] |
Gene, Accession # | [FLT3] |
Catalog # | MBS5313777 |
Price | $375 |
Order / More Info | FLT3 (Tyr591) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |