PKC epsilon Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPKC epsilon
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Protein kinase C epsilon type(PRKCE) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Protein kinase C epsilon type, also known as PKCE, is an enzyme that in humans is encoded by the PRKCE gene. The protein encoded by this gene is one of the PKC family members. PRKCE is mapped to 2p21. This kinase has been shown to be involved in many different cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. It has been found that activation of PRKCE can induce VR1 channel activity at room temperature in the absence of any other agonist. PRKCE gene plays a role in apoptosis signaling pathways in thyroid cells and it has
ImmunogenImmunogen: E Coli-derived human PKC epsilon recombinant protein (Position: Q53-R236). Human PKC epsilon shares 99% amino acid (aa) sequence identity with both mouse and rat PKC epsilon. Ig Type: Rabbit IgG
Other Names[Protein kinase C epsilon type; KPCE_HUMAN; MGC125656; MGC125657; nPKC epsilon; nPKC-epsilon; PKCE; Pkcea; PRKCE; Protein kinase C epsilon; Protein kinase C epsilon type; protein kinase C, epsilon], [PRKCE; PRKCE; PKCE; nPKC-epsilon; PKCE]
Gene, Accession #[PKC epsilon], Gene ID: 5581, NCBI: NP_005391.1, UniProt: Q02156
Catalog #MBS178262
Price$315
Order / More InfoPKC epsilon Antibody from MYBIOSOURCE INC.
Product Specific References1. Basta P, Strickland MB, Holmes W, Loomis CR, Ballas LM, Burns DJ (Nov 1992). Sequence and expression of human protein kinase C-epsilon. Biochim Biophys Acta 1132 (2): 154-60. 2. Knauf, J. A., Elisei, R., Mochly-Rosen, D., Liron, T., Chen, X.-N., Gonsky, R., Korenberg, J. R., Fagin, J. A. Involvement of protein kinase C-epsilon (PKC-epsilon) in thyroid cell death: a truncated chimeric PKC-epsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis. J. Biol. Chem. 274: 23414-23425, 1999. 3. Premkumar, L. S., Ahern, G. P. Induction of vanilloid receptor channel activity by protein kinase C. Nature 408: 985-990, 2000.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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