Neuropilin 1 (CT) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNeuropilin 1 (CT)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, bovine
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes ~130 kDa of human Neuropilin1 protein. The other species are not tested. The neuropilin-1 (Nrp1) is a multifunctional protein, identified principally as a receptor for the class 3 semaphorins and members of the vascular endothelial growth factor (VEGF) family, but it is capable of other interactions. It is a marker of regulatory T cells (Tr), which often carry Nrp1 and latency-associated peptide (LAP)-TGF-beta1 (the latent form). Nrp1 is reported to be expressed in breast cancer cells. The ischemia can increase neuropilin 1 protein expression in experimental rat brain as well.
ImmunogenAntigen Preparation: A synthetic peptide corresponding to the C-terminus of human Neurpilin1 protein. This sequence is identical among human and bovine.
Other Names[Rabbit Neuropilin1; CD304 antigen; NRP1; VEGF Receptor], [NRP1; NRP1; NP1; NRP; BDCA4; CD304; VEGF165R; DKFZp781F1414; DKFZp686A03134; NRP; VEGF165R]
Gene, Accession #[Neuropilin-1 (CT)], Gene ID: 8829, NCBI: NP_003864.4, UniProt: O14786
Catalog #MBS462090
Price$285
Order / More InfoNeuropilin 1 (CT) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesEldar Hochman et al. Molecular Pathways Regulating Pro-migratory Effects of Hedgehog Signaling. J. Biol. Chem., Vol. 281, Issue 45, 33860-33870, November 10, 2006 Glinka Y, et al. Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity. J Leukoc Biol. 2008 Jul; 84 (1): 302-10. Epub 2008 Apr 24
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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