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Antigenic Specificity | GAD1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against GAD1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GAD1 |
Other Names | [glutamate decarboxylase 1 isoform GAD67; Glutamate decarboxylase 1; glutamate decarboxylase 1; glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform] |
Gene, Accession # | [GAD1], Gene ID: 2571, NCBI: NP_000808, UniProt: Q99259 |
Catalog # | MBS3211617 |
Price | $335 |
Order / More Info | GAD1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |