Edit |   |
---|---|
Antigenic Specificity | MAGEA1 (Center), 143-173 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAGEA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-173 amino acids from the Central region of human MAGEA1. MAGEA1 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis |
Immunogen | n/a |
Other Names | [Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 11; CT11; MAGE-1 antigen; MAGEA1; MAGE1; MAGE1A] |
Gene, Accession # | [MAGEA1], Gene ID: 4100, NCBI: NP_004979.3, UniProt: P43355 |
Catalog # | MBS9212065 |
Price | $165, $370 |
Order / More Info | MAGEA1 (Center), 143-173 Antibody from MYBIOSOURCE INC. |
Product Specific References | Suyama, T., et al., Leuk. Res. 26(12):1113-1118 (2002). Mallon, A.M., et al., Genome Res. 10(6):758-775 (2000). Rogner, U.C., et al., Genomics 29(3):725-731 (1995). Schultz-Thater, E., et al., Int. J. Cancer 59(3):435-439 (1994). Celis, E., et al., Mol. Immunol. 31(18):1423-1430 (1994). |