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Antigenic Specificity | THAP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 0.5-1.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.Structure: Belongs to the THAP1 family.Expression: Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 150-210 on human THAP domain-containing protein 1. Conjugation: Unconjugated |
Other Names | [Affinity Purified THAP domain-containing protein 1; Nuclear proapoptotic factor; THAP 1; THAP domain containing apoptosis associated protein 1; THAP domain containing protein 1; THAP domain protein 1] |
Gene, Accession # | [THAP1], Gene ID: 55145, NCBI: NP_060575.1, UniProt: Q9NVV9 |
Catalog # | MBS5400825 |
Price | $390 |
Order / More Info | THAP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |