THAP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTHAP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshumanpredicted: mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.1 mg
Concentration0.5-1.5 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC)
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DescriptionOverview: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.Structure: Belongs to the THAP1 family.Expression: Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 150-210 on human THAP domain-containing protein 1. Conjugation: Unconjugated
Other Names[Affinity Purified THAP domain-containing protein 1; Nuclear proapoptotic factor; THAP 1; THAP domain containing apoptosis associated protein 1; THAP domain containing protein 1; THAP domain protein 1]
Gene, Accession #[THAP1], Gene ID: 55145, NCBI: NP_060575.1, UniProt: Q9NVV9
Catalog #MBS5400825
Price$390
Order / More InfoTHAP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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