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Antigenic Specificity | Histone H3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, other |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of HeLa cell line and H3 protein expressed in E.coli., using Histone H3 antibody. Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin (1). The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination (2-5). These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression (6). In most |
Immunogen | Immunogen: Recombinant protein of human Histone H3 |
Other Names | [histone H3; Histone H3.3] |
Gene, Accession # | NCBI: BAA31218.1 |
Catalog # | MBS4150058 |
Price | $385 |
Order / More Info | Histone H3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |