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Antigenic Specificity | Mouse CD210 |
Clone | [1B1.3A] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10. |
Immunogen | n/a |
Other Names | [Mouse CD210; Interleukin-10 receptor subunit alpha; Il10ra; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD210; Il10ra] |
Gene, Accession # | [CD210], Gene ID: 16154, NCBI: NP_032374.1, UniProt: Q61727 |
Catalog # | MBS2553805 |
Price | $85, $100 |
Order / More Info | Mouse CD210 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Ho A, et al. 1993. P. Natl. Acad. Sci. USA 90:11267. 2. Tan JC, et al. 1993. J. Biol. Chem. 268:21053. 3. Niemand C, et al. 2003. J. Immunol. 170:3263. 4. Corinti S, et al. 2001. J. Immunol. 166:4312. |