TNF alpha (Infliximab); Human IgG1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-TNF alpha (Infliximab); Human IgG1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | TNF alpha (Infliximab); Human IgG1 |
| Clone | [cA2] |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein A purified |
| Size | 0.2 mg |
| Concentration | n/a |
| Applications | ELISA (EIA); In Vivo; Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody to detect TNF alpha in human samples. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia; Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Upregulates the expression of protein phosphatase 1 (PP1); which dephosphorylates the key 'Ser-418' residue of FOXP3; thereby inactivating FOXP3 and rendering Treg cells functionally defecti |
| Immunogen | Immunogen: Purified recombinant human TNF (rTNF) |
| Other Names | [TNF-alpha; TNFalpha; TNFSF; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; TNFa], [TNF; TNF; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2] |
| Gene, Accession # | [TNF alpha], Gene ID: 7124, NCBI: NP_000585.2, UniProt: P01375 |
| Catalog # | MBS845975 |
| Price | $655 |
| Order / More Info | TNF alpha (Infliximab); Human IgG1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies