Human Platelet Factor 4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Platelet Factor 4
Clone[RTO]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2bkappa
Formatbiotin conjugate
Size0.1 mg
Concentration0.1 mg/ml
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionThis antibody is specific for Human Platelet Factor IV. Platelet factor IV is a 70 aa protein released from the alpha granules of activated platelets. PF4 is synthesized by bone marrow megakaryocytes and stored in alpha granules as a non-covalent bound tetramer. Platelet factor IV binds with high affinity to heparin and plays a role in inflammation and wound repair. PF4 is a chemoattractant for neutrophils, monocytes and fibroblasts and has been reported to be an immunologic regulator that inhibits suppressor T-cell activity. (clone RTO) is seen to bind free PF4 in the absence of any bound heparin. This is unlike (clone KKO), which binds PF4/heparin complexes to a similar degree as auto-antibodies found in individuals with Heparin-Induced T
ImmunogenImmunogen: Human Factor IV purified from the supernatant of thrombin activated platelets.
Other Names[Platelet Factor 4, Biotin (Clone: RTO) (Mouse IgG2b); Human Platelet Factor IV], [PF4V1; PF4V1; PF4A; CXCL4L1; CXCL4V1; PF4-ALT; SCYB4V1; CXCL4V1; SCYB4V1]
Gene, Accession #Gene ID: 5197, NCBI: AAA60067.1, UniProt: P10720
Catalog #MBS520471
Price$325
Order / More InfoHuman Platelet Factor 4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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