Phospho-CBL (Tyr674) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-CBL (Tyr674) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-CBL (Tyr674) antibody detects endogenous levels of CBL only when phosphorylated at Tyrosine 674. Description: Cbl an adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface.Function: Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and ter |
| Immunogen | Immunogen: A synthesized peptide derived from human CBL around the phosphorylation site of Tyrosine 674 Subcellular Location: Cytoplasm. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (92%), Zebrafish (92%), Bovine (92%), Horse (92%), Sheep (92%), Rabbit (92%), Dog (92%), Chicken (100%), Xenopus (92%) |
| Other Names | [4732447J05Rik; C CBL; Cas Br M (murine) ecotropic retroviral transforming sequence; Casitas B lineage lymphoma proto oncogene; Casitas B-lineage lymphoma proto-oncogene; CBL 2; cbl; CBL_HUMAN; CBL2; E3 ubiquitin protein ligase CBL; E3 ubiquitin-protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; Proto-oncogene c-CBL; RGD1561386; RING finger protein 55; RNF55; Signal transduction protein CBL] |
| Gene, Accession # | [CBL], Gene ID: 867, NCBI: NP_005179.2, UniProt: P22681 |
| Catalog # | MBS9600996 |
| Price | $240, $280 |
| Order / More Info | Phospho-CBL (Tyr674) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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