COPS7A (C-term), 237-266 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | COPS7A (C-term), 237-266 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This COPS7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the C-terminal region of human COPS7A. Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of |
| Immunogen | n/a |
| Other Names | [COP9 signalosome complex subunit 7a; SGN7a; Signalosome subunit 7a; Dermal papilla-derived protein 10; JAB1-containing signalosome subunit 7a; COPS7A; CSN7A; DERP10] |
| Gene, Accession # | [COPS7A], Gene ID: 50813, NCBI: NP_001157565.1, UniProt: Q9UBW8 |
| Catalog # | MBS9215100 |
| Price | $165, $370 |
| Order / More Info | COPS7A (C-term), 237-266 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Stelzl, U., et al. Cell 122(6):957-968(2005) Obuse, C., et al. Nat. Cell Biol. 6(11):1135-1141(2004) Wolf, D.A., et al. Nat. Cell Biol. 5(12):1029-1033(2003) Groisman, R., et al. Cell 113(3):357-367(2003) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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