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Antigenic Specificity | RNASEH1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes; two of them are at different locations of chro |
Immunogen | Immunogen: Recombinant protein of human RNASEH1 (NP 002927.2). |
Other Names | [ribonuclease H1 isoform 1; Ribonuclease H1; ribonuclease H1; ribonuclease H1; Ribonuclease H type II] |
Gene, Accession # | [RNASEH1], Gene ID: 246243, NCBI: NP_002927, UniProt: O60930 |
Catalog # | MBS8574162 |
Price | $280 |
Order / More Info | RNASEH1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |