SAP102 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SAP102 |
| Clone | [S19-2] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.025 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Microarray (AM) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~105kDa. No cross-reactivity against PSD95, SAP97 or Chapsyn-110. Synapse-associated protein 102 belongs to the membrane-associated guanylate kinase protein family and is a homolog of the Drosophila dis large tumor suppressor protein. SAP102 has extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminal (1, 2). SAP102 consists of three 90 amino acids PDZ domains at its amino terminus, a Src homology 3 domain and a guanylate kinase domain (3). All three PDZ domains of SAP102 participate in binding to the NMDA reception, interacting specifically with the carboxy-terminal domain of the N-methyl-D-aspartate receptor 2B (NR2B). The interaction may facilitate AMPA receptor with |
| Immunogen | Immunogen: Fusion protein amino acids 1-120 of rat SAP102 Immunogen Species: Rat |
| Other Names | [Mouse Rat SAP102 IgG1; SAP102, Clone S19-2; DLG3; MRX90; NEDLG; XLMR; Disks large homolog 3; PSD-95/SAP90-related protein 1; Synapse-associated protein 102; SAP-102] |
| Gene, Accession # | [SAP102], Gene ID: 58948, NCBI: Q62936.1, UniProt: Q62936 |
| Catalog # | MBS8001886 |
| Price | $205 |
| Order / More Info | SAP102 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Muller B.M., et al. (1996) Neuron 17: 255-265. 2. Lau L. F., et al. (1996) J. Biol. Chem. 271: 21622-21628. 3. Cuthbert P.C., et al. (2007) J Neuroscience 27:2673-2682. 4. Lau L.F., et al. (1996) J Biol Chem 274:5782-5790. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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