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Antigenic Specificity | Bak |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bak Polyclonal Antibody detects endogenous levels of Bak protein. The protein encoded by BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein (BCL2 antagonist/killer 1) localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Bak at AA range: 1-80 |
Other Names | [Rabbit Bak; BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7] |
Gene, Accession # | [Bak], Gene ID: 578, NCBI: NP_001179.1, UniProt: Q16611 |
Catalog # | MBS9701478 |
Price | $130, $220, $325 |
Order / More Info | Bak Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |