SATB2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySATB2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: At least two isoforms of SATB2 are known to exist. This SATB2 antibody will not cross-react with SATB1. Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcript
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide near the amino terminus of the human SATB2.
Other Names[DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2]
Gene, Accession #[SATB2], Gene ID: 23314, NCBI: NP_001165980.1, UniProt: Q9UPW6
Catalog #MBS9402904
Price$320
Order / More InfoSATB2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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