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Antigenic Specificity | SATB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of SATB2 are known to exist. This SATB2 antibody will not cross-react with SATB1. Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcript |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide near the amino terminus of the human SATB2. |
Other Names | [DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2] |
Gene, Accession # | [SATB2], Gene ID: 23314, NCBI: NP_001165980.1, UniProt: Q9UPW6 |
Catalog # | MBS9402904 |
Price | $320 |
Order / More Info | SATB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |