Tuberin (TSC2) (S1798), 1776-1805 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Tuberin (TSC2) (S1798), 1776-1805 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Tuberin (TSC2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1776-1805 amino acids from human Tuberin (TSC2). Mutations in TSC2 lead to tuberous sclerosis complex. This protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. |
| Immunogen | n/a |
| Other Names | [Tuberin; Tuberous sclerosis 2 protein; TSC2; TSC4] |
| Gene, Accession # | [TSC2], Gene ID: 7249, NCBI: NP_000539.2, UniProt: P49815 |
| Catalog # | MBS9211633 |
| Price | $165, $370 |
| Order / More Info | Tuberin (TSC2) (S1798), 1776-1805 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Li, Y., et al., Mol. Cell. Biol. 24(18):7965-7975 (2004). Karbowniczek, M., et al., J. Biol. Chem. 279(29):29930-29937 (2004). Corradetti, M.N., et al., Genes Dev. 18(13):1533-1538 (2004). Birchenall-Roberts, M.C., et al., J. Biol. Chem. 279(24):25605-25613 (2004). Lewis, J.C., et al., J. Med. Genet. 41(3):203-207 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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