PKR-like Endoplasmic Reticulum Kinase Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PKR-like Endoplasmic Reticulum Kinase |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.1 mL |
| Concentration | 1ug/ul |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antiserum is directed against PERK and reacts with the PERK from mouse tissues. Reactivity to other species is unknown. The PKR-like endoplasmic reticulum kinase (PERK, also know as Eukaryotic translation initiation factor 2-alpha kinase 3) is a type I transmembrane protein localized to the endoplasmic reticulum (ER). PERK consists of an N-terminal ER luminal domain, a membrane-spanning region, and a cytosolic C-terminal serine/threonine kinase domain (1). The luminal domain of PERK is bound to the ER chaperone GRP78 in unstressed cells (2). PERK activation occurs upon accumulation of misfolded proteins and the ER lumen, which triggers GRP78 dissociation from PERK thereby allowing PERK dimerization and autophosphorylation (3, 4). PERK |
| Immunogen | Immunogen: This whole rabbit serum was prepared by repeated immunizations with a recombinant fusion protein from amino acids 601-1115 of mouse deltaN PERK (see link below for the full length sequence of the mouse gene product). |
| Other Names | [PKR-like endoplasmic reticulum kinase; eukaryotic translation initiation factor 2-alpha kinase 3] |
| Gene, Accession # | Gene ID: 101171373 |
| Catalog # | MBS4158618 |
| Price | $540 |
| Order / More Info | PKR-like Endoplasmic Reticulum Kinase Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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