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Antigenic Specificity | Human Bile acid receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus. |
Immunogen | Immunogen: Recombinant human Bile acid receptor protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1205 / sc-1204 / sc-13063 |
Other Names | [Farnesoid X-activated receptor; Farnesol receptor HRR-1; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor-interacting protein 14; RXR-interacting protein 14; NR1H4; BAR; FXR; HRR1; RIP14], [NR1H4; NR1H4; BAR; FXR; HRR1; HRR-1; RIP14; BAR; FXR; HRR1; RIP14; RXR-interacting protein 14] |
Gene, Accession # | Gene ID: 9971, NCBI: NP_001193906.1, UniProt: Q96RI1 |
Catalog # | MBS1489037 |
Price | $160, $235 |
Order / More Info | Human Bile acid receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |