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Antigenic Specificity | STAT5A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STAT5A (Ab-780) antibody detects endogenous levels of total STAT5A protein. This gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse |
Immunogen | Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human STAT5A around the phosphorylation site of serine 780 (R-L-SP-P-P). |
Other Names | [STAT5A, partial; STAT5A; STAT5A], [STAT5A] |
Gene, Accession # | [STAT5A], NCBI: AHY20523.1 |
Catalog # | MBS416984 |
Price | $405 |
Order / More Info | STAT5A Antibody from MYBIOSOURCE INC. |
Product Specific References | Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944. |