STAT5A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySTAT5A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentration1ug/ul
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: STAT5A (Ab-780) antibody detects endogenous levels of total STAT5A protein. This gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse
ImmunogenImmunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human STAT5A around the phosphorylation site of serine 780 (R-L-SP-P-P).
Other Names[STAT5A, partial; STAT5A; STAT5A], [STAT5A]
Gene, Accession #[STAT5A], NCBI: AHY20523.1
Catalog #MBS416984
Price$405
Order / More InfoSTAT5A Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGouilleux F, et al. (1994) EMBO J. 13: 4361-4369.Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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