BCL-2 BINDING COMPONENT 3 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | BCL-2 BINDING COMPONENT 3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse (expected from sequence) |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Immunohistology Paraffin*, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises the p53 - upregulated modulator of apoptosis (PUMA), also known as Bcl-2 binding component 3. Bcl-2 binding component 3 is a pro-apoptotic member of the BCL-2 family.. . Bcl-2 binding component 3 is localised to the mitochondria, binds BCL-2 and induces cytochrome C release and apoptosis in response to p53. MBS221697 recognises the p53 - upregulated modulator of apoptosis (PUMA), also known as Bcl-2 binding component 3. Bcl-2 binding component 3 is a pro-apoptotic member of the BCL-2 family. Bcl-2 binding component 3 is localised to the mitochondria, binds BCL-2 and induces cytochrome C release and apoptosis in response to p53. |
| Immunogen | Immunogen: Synthetic peptide ARARQEGSSPEPVEG corresponding to the N-terminus of human Bcl-2 binding component 3. Histology Positive Control Tissue: Human breast carcinoma Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human Bcl-2 binding component 3 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
| Other Names | [bcl-2-binding component 3 isoform 1; Bcl-2-binding component 3; bcl-2-binding component 3; p53 up-regulated modulator of apoptosis; BCL2 binding component 3; JFY-1; p53 up-regulated modulator of apoptosis], [BBC3; BBC3; JFY1; PUMA; JFY-1; PUMA] |
| Gene, Accession # | [BCL-2], Gene ID: 27113, NCBI: NP_001120712.1, UniProt: Q9BXH1 |
| Catalog # | MBS221697 |
| Price | $375 |
| Order / More Info | BCL-2 BINDING COMPONENT 3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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