ZFAND5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ZFAND5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mL |
| Concentration | 1.2 mg/ml |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total ZFAND5 protein. Involved in protein degradation via the ubiquitin-proteasome system.May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy.Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. |
| Immunogen | Immunogen: Full length fusion protein of human ZFAND5 |
| Other Names | [ZA20D2; ZNF216; ZFAND5A] |
| Gene, Accession # | [ZFAND5], Gene ID: 7763, NCBI: NP_001095890.1, UniProt: O76080 |
| Catalog # | MBS9415402 |
| Price | $255 |
| Order / More Info | ZFAND5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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