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Antigenic Specificity | EED |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Polycomb protein EED(EED) detection. Tested with WB in Human;Rat. Background: Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. Furthermore, this protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two |
Immunogen | Immunogen: E Coli-derived human EED recombinant protein (Position: M256-R441). Human EED shares 100% amino acid (aa) sequence identity with mouse EED. Ig Type: Rabbit IgG |
Other Names | [Polycomb protein EED; eed; EED protein; EED, mouse, homolog of; EED_HUMAN; Embryonic ectoderm development; Embryonic ectoderm development isoform a; Embryonic ECTODERM development protein homolog; Embryonic ectoderm development protein, mouse, homolog of; HEED; OTTHUMP00000235483; OTTHUMP00000235484; OTTHUMP00000235485; Polycomb protein eed; WAIT 1; WAIT-1; WAIT1; WD protein associating with integrin cytoplasmic tails 1; embryonic ectoderm development], [EED; EED; HEED; WAIT1; hEED; WAIT-1] |
Gene, Accession # | [EED], Gene ID: 8726, NCBI: NP_001294936.1, UniProt: O75530 |
Catalog # | MBS177817 |
Price | $280 |
Order / More Info | EED Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: EED embryonic ectoderm development. 2. Rietzler M, Bittner M, Kolanus W, Schuster A, Holzmann B (Nov 1998). The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins. J. Biol. Chem. 273 (42): 27459-66. 3. Schumacher A, Lichtarge O, Schwartz S, Magnuson T (Jan 1999). The murine Polycomb-group gene eed and its human orthologue: functional implications of evolutionary conservation. Genomics 54(1): 79-88. |