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Antigenic Specificity | CHMP2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CHMP2B protein. This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CHMP2B. |
Other Names | [DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5] |
Gene, Accession # | [CHMP2B], Gene ID: 25978, NCBI: NP_001231573.1, UniProt: Q9UQN3 |
Catalog # | MBS9407178 |
Price | $255 |
Order / More Info | CHMP2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |