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Antigenic Specificity | ERBB3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-285 of human ERBB3 (NP 001973.2). |
Other Names | [HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3] |
Gene, Accession # | [ERBB3], Gene ID: 2065, NCBI: NP_001005915.1, UniProt: P21860 |
Catalog # | MBS8544137 |
Price | $280 |
Order / More Info | ERBB3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |