Edit |   |
---|---|
Antigenic Specificity | VGLL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2mg/mL |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could part |
Immunogen | Immunogen: Synthetic peptide of human VGLL1 |
Other Names | [Protein TONDU; TDU; TONDU; Transcription cofactor vestigial like protein 1; Transcription cofactor vestigial-like protein 1; Vestigial like 1; Vestigial like 1 homolog (Drosophila); Vgl-1; VGL1; Vgll1; VGLL1] |
Gene, Accession # | [VGLL1], Gene ID: 51442, NCBI: NP_057351.1, UniProt: Q99990 |
Catalog # | MBS2563100 |
Price | $110, $150, $225 |
Order / More Info | VGLL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |